The Center for Biostatistics in AIDS Research (CBAR), an organization within the Harvard T.H. Chan School of Public Health, is responsible for the design, monitoring and statistical analysis of clinical trials and observational studies for several major national and international NIH-funded clinical research networks. CBAR employs over 70 statisticians and epidemiologists including Harvard faculty, research scientists and staff. Investigators within CBAR have provided statistical leadership and support for clinical research networks for more than twenty five years. Currently this includes infectious disease networks such as: the AIDS Clinical Trials Network (ACTG), the International Maternal Pediatric Adol