At Boston Children's Hospital, success is measured in patients treated, parents comforted and teams taught. It's in discoveries made, processes perfected, and technology advanced. In major medical breakthroughs and small acts of kindness. And in colleagues who have your back and patients who have your heart. As a teaching hospital of Harvard Medical School, our reach is global and our impact is profound. Join our acclaimed team and discover how your talents can change lives. Yours included.
Dr. Leslie Kean's Lab is looking for a highly motivated individual with computational background to join our translational research and lead joint efforts of ongoing and new collaborative projects between the Kean Lab (Boston Children's Hospital and Dana Farber Cancer Institute), Ordovas-Montanes Lab (Boston Children's Hospital, Broad Institute, and Harvard Stem Cell Institute) and the Shalek Lab (MIT, Broad Institute, and Ragon Institute). Work is focused on applying computational pipelines and analytical tools for clinical studies involving single-cell RNAseq at scale.
Principal duties and responsibilities include: - Annotation and deposition of large-scale data sets from clinical collaborators on a continuing basis
- Developing computational pipelines for large-scale single-cell RNAseq data analysis (statistical framework, PCA, tSNE)
- Initial interpretation of data and visualization for dissemination within the lab and to collaborators
- Server and cloud-based platform storage management
- Server and cloud-based pipeline implementation
- Data analysis involving bash, python, R, javascript
- Automation of data analyses in projects with continuous data acquisition (e.g. longitudinal cohorts)
- Utilization of GitHub version control and integration
- Database administration and design using SQL and related platforms
- Building accessible interfaces for exploration of data by collaborators (e.g. GUIs)
Requirements - A Master's degree, with coursework in statistics and computer science and preferably in computational biology and related fields, e.g., mathematics, biostatistics, biology, chemistry, machine learning, and/or genomics
- At least two years' research experience; strong communication, time-management, and problem-solving skills
- The ability to learn quickly, balance project, work independently, and contribute to the lab environment.
- Knowledge of bash, python, R, and/or other programming languages required.
Please note: During a public health emergency, individuals in this role may be expected to take on additional duties to respond to organizational needs.
Please submit a cover letter with your application describing your current and future research interests.
Boston Children's Hospital offers competitive compensation and unmatched benefits, including a, affordable health, vision and dental insurance, generous levels of time off, 403(b) Retirement Savings plan, Pension, Tuition Reimbursement, and discounted rates on T-passes (50% off). Flexible schedule (if applicable). Discover your best.
Boston Children's Hospital is an Equal Opportunity / Affirmative Action Employer. Qualified applicants will receive consideration for employment without regard to their race, color, religion, national origin, sex, sexual orientation, gender identity, protected veteran status or disability. |
