Preclinical Researcher Center

The Researcher 3 will perform high-quality structured procedures in a fast-paced research laboratory setting. This position will be a part of a team working to develop and support innovative therapies for diseases with major public health significance. This research focuses on cardiovascular, neurologic, metabolic (e.g. diabetes and obesity), and infectious disease (e.g. COVID19). They will develop study protocols, review results, compile reports and collect data according to standard operating procedures and regulations. They will be responsible for communicating with the PI and management all study subject and protocol related correspondence. Various animal and in vitro models complement or are required for our biomedical research, with a parallel research program at this center that is focused on improving welfare/quality of life of study subjects used and enhancing the translational value of these models. As such, the employee must have interest in cooperative handling, enrichment, and behavioral management with study subjects. They may occasionally assist in induction, surgical procedures and post-operative care. The translational and high regulatory research completed at PCRC requires attention to detail and the ability to follow precise written protocols.
When not occupied with routine tasks, the employee is expected to participate in other lab tasks as assigned to advance the team’s work.

Salary will be commensurate with skills and experience.

Specific duties include:

Study Liaison – 50%
- Independently collect physiological data according to study protocols, analyze samples
- Sets up and operates laboratory equipment for collecting data, including basic equipment calibration and maintenance
- Prepares records for planned study procedures for hard copy data collection.
- Independently plan and execute in vitro work for complex study procedures.
- Manage the implementation of studies and perform a variety of medical procedures according to study protocols (i.e sample preparation for analysis, handling cells).
- Independently collect data related to procedures on detailed records, including recording of: study evaluations, procedures completed, supplies used, senior staff communications, budget, etc. by maintaining meticulous records and collection of data accurately in accordance with GLP guidelines.
- Data management, including maintaining accurate reports, collecting and analyzing data sets for publication and final reports.
- Critical disease model problem solving
- Organizes data into tables and text utilizing Microsoft Excel and Word; engage with senior staff and PI to ensure accurate interpretation and recording of data; maintain study subject research chart.
- Responsible for sensitive and confidential material.
- Conducts research in accordance with GLP regulations, maintain regulatory files
- Perform and assist with surgical induction and recovery of study subject if needed, as well as
with laboratory/surgical procedures including but not limited to, in vitro cell models, tissue analysis, imaging, and surgery
- Establish and maintain a working knowledge of the principles behind daily work.
- Review enrollment criteria to determine study subjects eligibility.
- Facilitate open and professional communication related to study subject and teamwork among a diverse team (researchers, students, DVMs, MDs)

Lab Technical Lead – 50%
- Develops skills that are cross functional and uses time efficiently including helping other areas of the lab.
- Find solutions to complex and routine technical or operational problems, typically resolving through standard operating procedures but will at times need to create novel solutions to complex problems.
- Maintains a clean environment and ensures that areas are adequately ordered, stocked and that instruments and equipment are in good working order.
- Calibrate equipment and be able to troubleshoot equipment properly
- Initiate and revise lab SOPs as needed
- Assemble instrument and packs as needed

- Develop protocols for process improvement projects.
- Participate in lab meetings/rounds
- Lead training and educational programs and tours
- Must adhere to safety and infection control policies and procedures.
- Review daily schedule, prioritize tasks to manage, coordinate, and alter order of work flow
- Other duties as assigned by supervisor or Director